HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 285 Hs			1 727
+	Hs
		451311 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		434429 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		932046 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		297568 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		297602 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		451225 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		434409 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		ABTB2_HUMAN (231-647): 1.15e-77: 271: 17.08
+	Hs
		418937 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		894128 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		925177 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		931991 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		894628 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		564571 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		564758 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		925356 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		545725 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		892702 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		925766 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		951494 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		901094 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29