HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 973
+	Hs
		657023 S10A1_HUMAN (1-90): 1.89e-33: 112: 36.17		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		686782 S10A4_HUMAN (1-93): 3.21e-32: 109: 27.84		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		731756 S10AB_HUMAN (2-93): 2.51e-32: 109: 26.04		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		682455 S100P_HUMAN (2-92): 2.81e-31: 106: 35.79		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736471 S100Z_HUMAN (1-93): 4.93e-30: 104: 28.87		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		706072 S10A2_HUMAN (1-92): 5.23e-30: 103: 27.08		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736462 S10A3_HUMAN (1-90): 2.03e-29: 102: 22.34		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		444914 S10A9_HUMAN (2-88): 1.26e-28: 101: 26.09		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736464 S10AA_HUMAN (1-93): 7.51e-29: 101: 24.74		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		407590 S100B_HUMAN (2-89): 9.64e-28: 98: 32.61		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		445135 S10A6_HUMAN (1-88): 1.68e-27: 97.2: 24.44		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736466 S10AC_HUMAN (2-89): 1.05e-26: 95.3: 38.04		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736461 S10A5_HUMAN (1-91): 1.36e-25: 92.6: 29.35		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736472 S10AD_HUMAN (2-80): 6.21e-23: 86: 23.75		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		736473 S10AE_HUMAN (3-80): 1.43e-21: 82.6: 20.25		NAC1_HUMAN (1-973): 0: 1124: 100.00
+	Hs
		711962 S100G_HUMAN (5-80): 6.54e-19: 75.3: 32.47		NAC1_HUMAN (1-973): 0: 1124: 100.00