HitPredict

Interactor 1: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Interactor 2: S10A3 (P33764)
Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3)
Gene: S100A3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 101
+	Hs
		657023 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A1_HUMAN (1-90): 1.78e-38: 125: 42.22
+	Hs
		686782 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A4_HUMAN (1-98): 1.54e-38: 125: 45.92
+	Hs
		731756 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AB_HUMAN (2-99): 2.87e-37: 122: 29.29
+	Hs
		706072 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A2_HUMAN (1-97): 1.12e-36: 121: 43.30
+	Hs
		682455 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100P_HUMAN (3-91): 5.35e-36: 119: 33.71
+	Hs
		736471 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100Z_HUMAN (1-90): 1.05e-34: 116: 37.78
+	Hs
		736464 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AA_HUMAN (1-90): 4.74e-34: 114: 27.78
+	Hs
		444914 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A9_HUMAN (3-97): 1.57e-33: 113: 30.21
+	Hs
		407590 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100B_HUMAN (3-91): 1.64e-32: 110: 38.20
+	Hs
		736466 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AC_HUMAN (3-91): 2.16e-31: 107: 31.46
+	Hs
		445135 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A6_HUMAN (1-92): 2.03e-30: 104: 44.57
+	Hs
		424146 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A8_HUMAN (1-97): 1.23e-29: 103: 20.62
+	Hs
		736461 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A5_HUMAN (1-90): 4.01e-27: 96.9: 42.22
+	Hs
		736472 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AD_HUMAN (3-84): 2.04e-25: 92.6: 30.49
+	Hs
		736470 NAC1_HUMAN (1-973): 0: 1124: 100.00		S1A7A_HUMAN (3-100): 5.04e-24: 89.2: 19.00
+	Hs
		724537 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A7_HUMAN (3-100): 3.34e-23: 87.2: 17.00
+	Hs
		736473 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AE_HUMAN (3-84): 1.11e-21: 83.4: 19.51
+	Hs
		711962 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100G_HUMAN (4-84): 2.6e-20: 79.2: 24.69