HitPredict

Interactor 1: ANXA2 (P07355)
Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)
Gene: ANXA2

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030496 - midbody and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 191
+	Hs
		843481 ANX11_HUMAN (15-339): 2.17e-178: 505: 46.46		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		427515 ANXA2_HUMAN (1-339): 3.16e-174: 488: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		427507 ANXA2_HUMAN (1-339): 3.16e-174: 488: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		64115 AXA2L_HUMAN (1-339): 5.8e-170: 477: 97.94		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		427408 ANXA2_HUMAN (1-339): 3.16e-174: 488: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		451790 ANXA4_HUMAN (25-339): 5.88e-173: 484: 49.52		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		444875 ANXA5_HUMAN (24-339): 5.27e-160: 451: 46.20		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		376210 ANXA1_HUMAN (1-338): 4.33e-159: 450: 50.72		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		436098 ANXA6_HUMAN (37-337): 1.36e-63: 215: 27.93		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82