Protein: RLA2
Large ribosomal subunit protein P2A (P2A) (60S acidic ribosomal protein P2-alpha) (A2) (L12eIB) (L44) (YP2alpha)

Gene: RLA2, RPP2A
Organism: Saccharomyces cerevisiae S288C
Interactions: 155
UniProt ID: P05319

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0002182 - cytoplasmic translational elongation
GO:0003735 - structural constituent of ribosome
GO:0022625 - cytosolic large ribosomal subunit
GO:0030295 - protein kinase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

427049

RLA0
Large ribosomal subunit protein uL10

5

3

Small-scale

0.921

High

383037

RLA4
Large ribosomal subunit protein P2B

5

4

Small-scale

0.904

High

427653

RLA3
Large ribosomal subunit protein P1B

4

8

Small-scale

0.881

High

427627

RLA2
Large ribosomal subunit protein P2A

2

4

Small-scale

0.743

High

427505

RLA1
Large ribosomal subunit protein P1A

1

8

Small-scale

0.618

High

391965

HSP82
ATP-dependent molecular chaperone HSP82

3

3

High-throughput

0.585

High

427753

RQC1
Ribosome quality control complex subunit 1

3

1

Small-scale

0.585

High

427673

RL16A
Large ribosomal subunit protein uL13A

2

4

High-throughput

0.584

High

427744

GCN5
Histone acetyltransferase GCN5

2

1

High-throughput

0.574

High

427677

HS104
Heat shock protein 104

2

2

High-throughput

0.533

High

427708

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

427639

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.489

High

427668

SGF29
SAGA complex subunit SGF29

1

1

High-throughput

0.489

High

427682

PP12
Serine/threonine-protein phosphatase PP1-2

1

1

High-throughput

0.489

High

427686

SPT7
SAGA complex subunit SPT7

1

3

High-throughput

0.489

High

427690

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

4

High-throughput

0.489

High

427695

RT107
Regulator of Ty1 transposition protein 107

1

1

Small-scale

0.489

High

427715

CLA4
Serine/threonine-protein kinase CLA4

1

2

High-throughput

0.489

High

427720

SPT20
SAGA complex subunit SPT20

1

1

High-throughput

0.489

High

427724

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

1

High-throughput

0.489

High

427727

SGF73
SAGA complex subunit SGF73

1

1

High-throughput

0.489

High

427733

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.489

High

427739

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.489

High

427741

ADA2
SAGA complex subunit ADA2

1

1

High-throughput

0.489

High

427745

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

1

High-throughput

0.489

High

427752

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.489

High

427770

SUS1
SAGA complex subunit SUS1

1

2

High-throughput

0.489

High

154098

RL36B
Large ribosomal subunit protein eL36B

1

4

High-throughput

0.479

High

383226

RL28
Large ribosomal subunit protein uL15

1

1

High-throughput

0.479

High

409640

RL24A
Large ribosomal subunit protein eL24A

1

3

High-throughput

0.479

High

409815

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

414960

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.479

High

427628

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

427629

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.479

High

427630

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.479

High

427631

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.479

High

427632

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

427633

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

427634

RL36A
Large ribosomal subunit protein eL36A

1

4

High-throughput

0.479

High

427635

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

427636

RL22A
Large ribosomal subunit protein eL22A

1

3

High-throughput

0.479

High

427641

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

427642

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

427644

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

427645

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

427646

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

427647

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

427648

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

427649

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

427654

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.479

High

427658

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.479

High

427659

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

427662

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.479

High

427665

RL24B
Large ribosomal subunit protein eL24B

1

3

High-throughput

0.479

High

427672

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

427674

RL16B
Large ribosomal subunit protein uL13B

1

4

High-throughput

0.479

High

427676

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.479

High

427687

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

427689

RL32
Large ribosomal subunit protein eL32

1

3

High-throughput

0.479

High

427693

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

427694

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.479

High

427704

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.479

High

427706

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

427709

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

427710

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.479

High

427711

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

427713

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

427717

RL37A
Large ribosomal subunit protein eL37A

1

3

High-throughput

0.479

High

427718

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

427721

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.479

High

427722

RL37B
Large ribosomal subunit protein eL37B

1

3

High-throughput

0.479

High

427728

RL26B
Large ribosomal subunit protein uL24B

1

3

High-throughput

0.479

High

427737

RL22B
Large ribosomal subunit protein eL22B

1

3

High-throughput

0.479

High

427738

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

427740

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.479

High

427742

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

427759

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

427767

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

427769

RL11B
Large ribosomal subunit protein uL5B

1

3

High-throughput

0.479

High

427680

RPD3
Histone deacetylase RPD3

1

3

Small-scale

0.457

High

427726

SNT2
E3 ubiquitin-protein ligase SNT2

1

1

Small-scale

0.457

High

427651

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

427655

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

427765

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.439

High

364215

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.437

High

427637

SC160
Protein SCP160

1

3

High-throughput

0.437

High

427638

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

3

High-throughput

0.437

High

427640

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.437

High

427656

PDR1
Transcription factor PDR1

1

1

High-throughput

0.437

High

427657

ACOX
Acyl-coenzyme A oxidase

1

2

High-throughput

0.437

High

427661

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

427664

RAD53
Serine/threonine-protein kinase RAD53

1

3

High-throughput

0.437

High

427666

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

427669

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

427670

CDC48
Cell division control protein 48

1

2

High-throughput

0.437

High

427671

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

427675

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

427679

ZUO1
Zuotin

1

4

High-throughput

0.437

High

427683

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.437

High

427685

IXR1
Intrastrand cross-link recognition protein

1

4

Small-scale

0.437

High

427688

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

427692

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.437

High

427698

STM1
Suppressor protein STM1

1

1

High-throughput

0.437

High

427699

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.437

High

427700

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

427701

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.437

High

427702

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.437

High

427705

TM108
Protein TMA108

1

2

High-throughput

0.437

High

427712

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

427714

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

427716

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

427725

VID30
GID complex subunit 1

1

1

High-throughput

0.437

High

427729

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.437

High

427730

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

427731

H1
Histone H1

1

1

High-throughput

0.437

High

427734

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

427735

JJJ1
J protein JJJ1

1

6

High-throughput

0.437

High

427736

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.437

High

427743

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

427746

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

427747

HMO1
High mobility group protein 1

1

4

High-throughput

0.437

High

427748

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.437

High

427749

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.437

High

427750

UTP14
U3 small nucleolar RNA-associated protein 14

1

1

High-throughput

0.437

High

427751

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.437

High

427754

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

427756

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.437

High

427757

SGO1
Shugoshin

1

1

High-throughput

0.437

High

427764

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

427766

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

427768

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.437

High

427678

EF2
Elongation factor 2

1

1

Small-scale

0.417

High

427643

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

427652

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

427667

SIS1
Protein SIS1

1

1

High-throughput

0.407

High

427681

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

427684

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

427707

DJP1
DnaJ-like protein 1

1

1

High-throughput

0.407

High

427719

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.407

High

427723

CWC23
Pre-mRNA-splicing factor CWC23

1

1

High-throughput

0.407

High

427760

HFI1
SAGA complex subunit HFI1

1

1

High-throughput

0.407

High

427660

HSP26
Heat shock protein 26

1

0

High-throughput

0.279

Low

427696

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.279

Low

427650

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

427763

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.251

Low

427663

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.249

Low

427691

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.249

Low

427697

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

427703

ARB1
ABC transporter ATP-binding protein ARB1

1

0

Small-scale

0.249

Low

427732

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.249

Low

427755

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

427758

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

427761

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

427762

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025