HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030838 - positive regulation of actin filament polymerization GO:0070062 - extracellular exosome GO:0070064 - proline-rich region binding and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 552
+	Hs
		430371 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		430234 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MTSS2_HUMAN (19-388): 2.46e-43: 166: 16.45
+	Hs
		430173 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SPTN1_HUMAN (3-442): 2.09e-42: 165: 11.85
+	Hs
		430183 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		LASP1_HUMAN (207-435): 2.59e-40: 148: 15.98
+	Hs
		430194 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18