Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC
Interactor 2: ARRB1 (Q8BWG8)
Beta-arrestin-1 (Arrestin beta-1)
Gene: ARRB1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19122674 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arrestin_C~SH3_1, Arrestin_N~SH3_1 |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025