Protein: ARRB2
Beta-arrestin-2 (Arrestin beta-2)

Gene: ARRB2
Organism: Mus musculus
Interactions: 19
UniProt ID: Q91YI4

Gene Ontology (top 5):
GO:0002031 - G protein-coupled receptor internalization
GO:0002092 - positive regulation of receptor internalization
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1274180

FFAR4
Free fatty acid receptor 4

1

12

Small-scale

0.665

High

999879

TRAF6
TNF receptor-associated factor 6

2

3

Small-scale

0.624

High

431365

SRC
Proto-oncogene tyrosine-protein kinase Src

1

8

Small-scale

0.618

High

1297487

ARRB1
Beta-arrestin-1

1

12

Small-scale

0.618

High

728534

AKT1
RAC-alpha serine/threonine-protein kinase

2

5

Small-scale

0.611

High

581967

INSR
Insulin receptor

1

4

Small-scale

0.536

High

1179281

GSK3A
Glycogen synthase kinase-3 alpha

1

4

Small-scale

0.501

High

1362397

GSK3B
Glycogen synthase kinase-3 beta

1

6

Small-scale

0.501

High

946615

CAR10
Caspase recruitment domain-containing protein 10

1

4

Small-scale

0.489

High

994024

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

Small-scale

0.480

High

662987

MDM2
E3 ubiquitin-protein ligase Mdm2

1

4

Small-scale

0.479

High

1028532

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

4

Small-scale

0.479

High

1297768

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.479

High

1298171

ITCH
E3 ubiquitin-protein ligase Itchy

1

6

Small-scale

0.479

High

1298403

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

5

Small-scale

0.479

High

1362396

NPHN
Nephrin

1

2

Small-scale

0.479

High

1362394

ATG5
Autophagy protein 5

1

0

Small-scale

0.458

High

1257339

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

Small-scale

0.292

High

1362395

ITA2B
Integrin alpha-IIb

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025