HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: KLH26 (Q53HC5)
Kelch-like protein 26
Gene: KLHL26

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 615
+	Hs
		431924 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH22_HUMAN (24-611): 0: 569: 32.32
+	Hs
		438235 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH22_HUMAN (24-611): 0: 569: 32.32
+	Hs
		432323 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH13_HUMAN (11-607): 6.82e-170: 500: 41.00
+	Hs
		432290 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLHL1_HUMAN (6-609): 6.7e-159: 475: 27.84
+	Hs
		431841 HS90A_HUMAN (1-732): 0: 1087: 100.00		KEAP1_HUMAN (6-610): 8.35e-159: 470: 25.53
+	Hs
		432055 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH36_HUMAN (22-608): 4.19e-156: 463: 35.08
+	Hs
		438236 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH26_HUMAN (1-615): 2.96e-166: 489: 100.00
+	Hs
		438163 HS90B_HUMAN (19-732): 0: 1059: 86.13		KEAP1_HUMAN (6-610): 8.35e-159: 470: 25.53
+	Hs
		438349 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH36_HUMAN (22-608): 4.19e-156: 463: 35.08
+	Hs
		432115 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLHL6_HUMAN (1-615): 2.32e-143: 431: 26.07
+	Hs
		432320 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH14_HUMAN (30-612): 1.63e-140: 424: 32.03
+	Hs
		438402 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLHL6_HUMAN (1-615): 2.32e-143: 431: 26.07
+	Hs
		432161 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH15_HUMAN (40-596): 1.23e-92: 299: 31.04
+	Hs
		432165 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH32_HUMAN (44-609): 1.91e-87: 286: 34.01
+	Hs
		438437 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH15_HUMAN (40-596): 1.23e-92: 299: 31.04
+	Hs
		438440 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH32_HUMAN (44-609): 1.91e-87: 286: 34.01
+	Hs
		432143 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH29_HUMAN (73-462): 8.46e-23: 105: 12.16
+	Hs
		431957 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH10_HUMAN (249-460): 9.14e-23: 104: 15.96
+	Hs
		438426 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH29_HUMAN (73-462): 8.46e-23: 105: 12.16
+	Hs
		438266 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH10_HUMAN (249-460): 9.14e-23: 104: 15.96