Interactor 1: RAF1 (P05625)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (C-MIL) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (RAF-1)
Gene: RAF1
Interactor 2: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF
Species: Gallus gallus
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27034005 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~C1_1, C1_1~PK_Tyr_Ser-Thr, C1_1~RBD, C1_1~Pkinase, PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~RBD, RBD~RBD |
| Common GO terms | GO:0000165 - MAPK cascade GO:0004709 - MAP kinase kinase kinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 4 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025