HitPredict

Interactor 1: HEPS (P05981)
Serine protease hepsin (EC 3.4.21.106) (Transmembrane protease serine 1) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]
Gene: HPN

Interactor 2: NFXL1 (Q6ZNB6)
NF-X1-type zinc finger protein NFXL1 (Ovarian zinc finger protein) (hOZFP)
Gene: NFXL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 911
+	Hs
		1252798 TM11B_HUMAN (153-403): 1.2e-101: 310: 40.00		NFXL1_HUMAN (1-911): 5.78e-149: 465: 100.00
+	Hs
		437665 HEPS_HUMAN (1-417): 5.68e-177: 501: 100.00		NOTC2_HUMAN (174-553): 8.41e-09: 61.9: 9.86
+	Hs
		1448854 TMPS4_HUMAN (13-406): 1.34e-123: 367: 32.49		JAG2_HUMAN (169-724): 3.95e-20: 98.5: 11.47
+	Hs
		1286958 TM11B_HUMAN (153-403): 1.2e-101: 310: 40.00		JAG2_HUMAN (169-724): 3.95e-20: 98.5: 11.47
+	Hs
		1047609 TM11B_HUMAN (153-403): 1.2e-101: 310: 40.00		NOTC2_HUMAN (174-553): 8.41e-09: 61.9: 9.86
+	Hs
		1490437 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		JAG2_HUMAN (169-724): 3.95e-20: 98.5: 11.47
+	Hs
		1461972 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		NOTC3_HUMAN (144-651): 3.64e-12: 73.1: 11.34
+	Hs
		1047649 PRS33_HUMAN (153-400): 2.42e-55: 186: 43.94		NOTC2_HUMAN (174-553): 8.41e-09: 61.9: 9.86
+	Hs
		1047790 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		NOTC2_HUMAN (174-553): 8.41e-09: 61.9: 9.86
+	Hs
		1366666 BSSP4_HUMAN (153-412): 8.58e-45: 159: 38.15		SORL_HUMAN (135-466): 2.83e-15: 83.1: 11.20