HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: KLH15 (Q96M94)
Kelch-like protein 15
Gene: KLHL15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 604
+	Hs
		438235 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH22_HUMAN (8-602): 0: 540: 29.56
+	Hs
		438440 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH32_HUMAN (9-593): 0: 529: 28.29
+	Hs
		431924 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH22_HUMAN (8-602): 0: 540: 29.56
+	Hs
		432165 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH32_HUMAN (9-593): 0: 529: 28.29
+	Hs
		432161 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH15_HUMAN (1-604): 1.79e-162: 479: 100.00
+	Hs
		438163 HS90B_HUMAN (1-724): 0: 1086: 100.00		KEAP1_HUMAN (3-603): 3.56e-147: 440: 23.06
+	Hs
		438349 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH36_HUMAN (2-591): 4.28e-147: 440: 26.25
+	Hs
		438555 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLHL1_HUMAN (8-593): 2.58e-145: 440: 22.11
+	Hs
		438266 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH10_HUMAN (19-592): 1.16e-142: 428: 22.76
+	Hs
		431841 HS90A_HUMAN (1-724): 0: 1072: 85.25		KEAP1_HUMAN (3-603): 3.56e-147: 440: 23.06
+	Hs
		432055 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH36_HUMAN (2-591): 4.28e-147: 440: 26.25
+	Hs
		431957 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH10_HUMAN (19-592): 1.16e-142: 428: 22.76
+	Hs
		438236 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH26_HUMAN (8-596): 3.6e-137: 414: 29.53
+	Hs
		431925 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH26_HUMAN (8-596): 3.6e-137: 414: 29.53
+	Hs
		438580 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH14_HUMAN (2-596): 4.04e-131: 399: 24.85
+	Hs
		438346 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH34_HUMAN (8-599): 1.7e-56: 203: 26.07
+	Hs
		432051 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH34_HUMAN (8-599): 1.7e-56: 203: 26.07
+	Hs
		438402 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLHL6_HUMAN (20-573): 9.8e-48: 178: 24.48
+	Hs
		432115 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLHL6_HUMAN (20-573): 9.8e-48: 178: 24.48
+	Hs
		438582 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH13_HUMAN (132-476): 1.01e-34: 141: 11.36