HitPredict

Interactor 1: INHBA (P08476)
Inhibin beta A chain (Activin beta-A chain) (Erythroid differentiation protein) (EDF)
Gene: INHBA

Interactor 2: CRDL2 (Q6WN34)
Chordin-like protein 2 (Breast tumor novel factor 1) (BNF-1) (Chordin-related protein 2)
Gene: CHRDL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15094188
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0030154 - cell differentiation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 429
+	Mm
		615510 BMP7_MOUSE (48-425): 2.83e-108: 327: 19.75		CRDL2_MOUSE (1-429): 5.38e-71: 231: 72.49
+	Mm
		823193 BMP5_MOUSE (6-425): 1.8e-107: 326: 18.95		CRDL2_MOUSE (1-429): 5.38e-71: 231: 72.49
+	Mm
		597616 BMP2_MOUSE (26-425): 7.46e-106: 320: 23.40		CRDL2_MOUSE (1-429): 5.38e-71: 231: 72.49
+	Mm
		597618 BMP4_MOUSE (23-425): 3.01e-95: 293: 20.57		CRDL2_MOUSE (1-429): 5.38e-71: 231: 72.49
+	Mm
		595651 BMP6_MOUSE (76-425): 7.9e-90: 283: 22.35		CRDL2_MOUSE (1-429): 5.38e-71: 231: 72.49
+	Mm
		792933 GDF5_MOUSE (21-425): 6.5e-81: 259: 19.29		CRDL2_MOUSE (1-429): 5.38e-71: 231: 72.49
+	Rn
		566271 TGFB1_RAT (46-426): 2.53e-90: 280: 22.53		Q71SA3_RAT (28-347): 9.54e-50: 183: 13.98
+	Hs
		351223 TGFB1_HUMAN (46-426): 1.91e-86: 270: 23.54		TSP1_HUMAN (28-347): 7.38e-50: 183: 13.68
+	Dm
		429968 DECA_DROME (18-425): 3.52e-94: 296: 22.46		SOG_DROME (28-334): 3.47e-35: 140: 23.31
+	Hs
		351256 TGFB1_HUMAN (46-426): 1.91e-86: 270: 23.54		TENX_HUMAN (79-403): 6.25e-32: 131: 12.47
+	Dm
		871198 SCW_DROME (59-425): 5.87e-79: 251: 16.09		SOG_DROME (28-334): 3.47e-35: 140: 23.31
+	Xl
		1265027 Q91597_XENLA (7-425): 6.55e-95: 292: 19.30		CHRD_XENLA (21-176): 3.16e-17: 86.2: 29.27
+	Dm
		429979 DECA_DROME (18-425): 3.52e-94: 296: 22.46		Q9W2H2_DROME (41-326): 2e-13: 74.2: 18.49
+	Mm
		597617 BMP4_MOUSE (23-425): 3.01e-95: 293: 20.57		BMPER_MOUSE (92-329): 6.49e-12: 69.6: 20.08
+	Hs
		155756 GDF8_HUMAN (6-426): 7.79e-95: 291: 21.30		LAMB2_HUMAN (164-360): 3.6e-09: 61.1: 11.96
+	Mm
		380162 TGFB1_MOUSE (46-426): 3.14e-90: 280: 22.28		CO1A1_MOUSE (29-103): 3.94e-10: 64.2: 30.26
+	Dm
		646121 60A_DROME (57-425): 1.92e-83: 264: 19.18		Q9W2H2_DROME (41-326): 2e-13: 74.2: 18.49
+	Hs
		351222 TGFB1_HUMAN (46-426): 1.91e-86: 270: 23.54		LAMB1_HUMAN (164-363): 8.91e-11: 66.1: 10.85
+	Hs
		885343 INHBE_HUMAN (35-426): 2.5e-74: 237: 28.83		FRAS1_HUMAN (23-354): 1.02e-11: 69.2: 12.96