HitPredict - High confidence protein-protein interactions

Interactor 1: CD14 (P08571)
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form]
Gene: CD14

Interactor 2: LBP (P18428)
Lipopolysaccharide-binding protein (LBP)
Gene: LBP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.55	0.632

Property	Details
Experiments	12417309, 7583357, 2402637
Identification Methods	pull down, biochemical, surface plasmon resonance
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001530 - lipopolysaccharide binding GO:0002752 - cell surface pattern recognition receptor signaling pathway GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0032757 - positive regulation of interleukin-8 production and 7 others more... GO:0032760 - positive regulation of tumor necrosis factor production GO:0034145 - positive regulation of toll-like receptor 4 signaling pathway GO:0045087 - innate immune response GO:0070062 - extracellular exosome GO:0070891 - lipoteichoic acid binding GO:0071222 - cellular response to lipopolysaccharide GO:0071223 - cellular response to lipoteichoic acid
Homologous interactions	0

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Last updated: 15 Jul 2024