HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: YTHD2 (Q9Y5A9)
YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Gene: YTHDF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29802200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 579
+	Hs
		516767 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		1031506 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		516575 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		442277 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		516679 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		236153 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		442468 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		1031376 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		1031449 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		963542 TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		235930 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		236047 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		442407 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		YTDC1_HUMAN (341-575): 6.57e-57: 205: 23.24
+	Hs
		442495 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50
+	Hs
		1288616 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		YTDC1_HUMAN (341-575): 6.57e-57: 205: 23.24
+	Hs
		1288629 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50
+	Sp
		252570 YKCG_SCHPO (100-248): 5.25e-33: 130: 21.48		MMI1_SCHPO (194-544): 2.12e-42: 160: 16.71
+	Hs
		236073 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50
+	Hs
		516595 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		KMT2C_HUMAN (7-383): 1.97e-13: 76.1: 14.92