Interactor 1: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2

Interactor 2: MCM10 (P32354)
Minichromosome maintenance protein 10 (Protein DNA43)
Gene: MCM10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 9154825, 27751725, 28510759, 19917723, 37968396, 26686640, 26719337, 28270517, 30598452, 22433841
Identification Methods two hybrid, affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0006271 - DNA strand elongation involved in DNA replication
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 868
Sc

1 571
+ Hs
+ Sc
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp
+ Sp
+ Sc
+ Sc

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Last updated: 15 Jul 2024