HitPredict

Interactor 1: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Interactor 2: MED28 (Q9H204)
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Gene: MED28

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16964398
Identification Methods	affinity chromatography technology, peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 178
+	Hs
		523146 SRC_HUMAN (1-524): 0: 582: 54.51		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		411851 LCK_HUMAN (23-526): 0: 581: 64.89		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		433471 YES_HUMAN (1-524): 0: 570: 56.77		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		412351 FYN_HUMAN (22-524): 0: 564: 57.79		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Mm
		763402 FYN_MOUSE (22-524): 0: 564: 57.60		MED28_MOUSE (1-178): 8.45e-99: 284: 94.38
+	Hs
		789091 ABL2_HUMAN (17-523): 5.55e-166: 503: 38.06		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		789008 TEC_HUMAN (3-520): 3.4e-162: 476: 34.20		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		986396 BTK_HUMAN (19-519): 1.38e-155: 460: 33.52		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00