HitPredict

Interactor 1: RAP1 (P08645)
Ras-related protein Rap1 (EC 3.6.5.2) (Rap1 GTPase) (Ras-like protein 3)
Gene: RAP1

Interactor 2: Q9VFD3 (Q9VFD3)
Uncharacterized protein, isoform B
Gene: DmelCG42788

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	15710747
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras, PDZ~Ras, RA~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Dm			1 1560
+	Dm
		332224 O96692_DROME (1-184): 1.13e-57: 180: 55.98		Q9VFD3_DROME (1-1560): 0: 1669: 100.00
+	Hs
		914374 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		E41L5_HUMAN (354-1041): 3.16e-108: 363: 15.05
+	Hs
		895282 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		E41L5_HUMAN (354-1041): 3.16e-108: 363: 15.05
+	Dm
		185669 O18335_DROME (4-176): 6.54e-75: 225: 31.03		MOEH_DROME (393-947): 3.91e-89: 304: 13.96
+	Hs
		914356 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		E41L1_HUMAN (331-1022): 1.96e-81: 290: 12.27
+	Hs
		204641 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		E41L2_HUMAN (236-942): 3.11e-81: 292: 12.20
+	Hs
		895272 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		E41L1_HUMAN (331-1022): 1.96e-81: 290: 12.27
+	Hs
		719572 RIT1_HUMAN (2-180): 3.94e-61: 190: 50.00		MERL_HUMAN (372-922): 7.57e-89: 304: 12.37
+	Hs
		505614 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		EPB41_HUMAN (324-945): 4.05e-74: 268: 12.22
+	Hs
		349889 RASK_HUMAN (1-182): 1.14e-56: 178: 55.50		MOES_HUMAN (391-884): 2.98e-92: 313: 13.86
+	Hs
		505642 RB11B_HUMAN (4-176): 1.4e-73: 222: 29.89		EPB41_HUMAN (324-945): 4.05e-74: 268: 12.22
+	Hs
		505601 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		EPB41_HUMAN (324-945): 4.05e-74: 268: 12.22
+	Hs
		349925 RASK_HUMAN (1-182): 1.14e-56: 178: 55.50		MERL_HUMAN (372-922): 7.57e-89: 304: 12.37
+	Hs
		204589 RASK_HUMAN (1-182): 1.14e-56: 178: 55.50		E41L2_HUMAN (236-942): 3.11e-81: 292: 12.20
+	Dm
		114271 O96692_DROME (1-184): 1.13e-57: 180: 55.98		M9PBW9_DROME (371-883): 4.21e-71: 267: 13.95
+	Hs
		349830 RASK_HUMAN (1-182): 1.14e-56: 178: 55.50		EPB41_HUMAN (324-945): 4.05e-74: 268: 12.22
+	Hs
		845887 RAB13_HUMAN (4-178): 6.55e-75: 224: 34.09		WWOX_HUMAN (173-338): 5.83e-45: 170: 23.46
+	Dm
		332243 O96692_DROME (1-184): 1.13e-57: 180: 55.98		Q9W2L2_DROME (18-248): 1.09e-53: 208: 22.89
+	Mm
		808365 RAP2A_MOUSE (1-171): 1.8e-62: 192: 62.79		NEDD4_MOUSE (110-265): 9.79e-21: 101: 23.43
+	Hs
		486014 RAP2A_HUMAN (1-171): 1.39e-59: 185: 62.79		NEDD4_HUMAN (157-265): 9.32e-20: 98.7: 23.58