HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 248
+	Hs
		409015 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		409044 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		409047 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		569067 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Mm
		372933 GFAP_MOUSE (80-465): 2.2e-129: 383: 61.14		1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96
+	Hs
		443445 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		684061 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		443452 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		409008 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		569050 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		409014 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		409042 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		409055 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		443346 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		443356 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		443441 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		443469 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Rn
		677657 VIME_RAT (14-466): 1.07e-109: 334: 97.35		1433B_RAT (1-239): 5.05e-100: 293: 69.04
+	Hs
		646928 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		904613 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16