HitPredict

Interactor 1: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 473 Hs			1 745
+	Hs
		359342 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		531467 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		445040 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		445043 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		445042 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		531360 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		359341 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		359344 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		359343 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		444365 K1C19_HUMAN (106-434): 2.34e-146: 425: 69.61		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		531466 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		1041625 K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		531469 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		531468 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		531359 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		531362 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		531363 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		531361 K1C10_HUMAN (112-422): 7.57e-130: 390: 67.52		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		359394 K1C14_HUMAN (1-448): 6.76e-154: 447: 83.48		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		531503 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		CUL5_HUMAN (7-745): 0: 627: 26.69