Interactor 1: EI2BG (P09032)
Translation initiation factor eIF2B subunit gamma (GCD complex subunit GCD1) (Guanine nucleotide exchange factor subunit GCD1) (eIF2B GDP-GTP exchange factor subunit gamma)
Gene: GCD1

Interactor 2: EI2BA (P14741)
Translation initiation factor eIF2B subunit alpha (GCD complex subunit GCN3) (Guanine nucleotide exchange factor subunit GCN3) (Translational activator GCN3) (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: GCN3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 8336705, 8887689, 9472020, 11805837, 11805826, 16554755, 16429126, 24852487, 22238343, 37968396
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 578
Sc

1 305
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sp
+ Sc

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Last updated: 15 Jul 2024