Interactor 1: STE7 (P06784)
Serine/threonine-protein kinase STE7 (EC 2.7.12.2)
Gene: STE7

Interactor 2: STE11 (P23561)
Serine/threonine-protein kinase STE11 (EC 2.7.11.25)
Gene: STE11

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.914

The method score is based on:

Property Details
Experiments 8816472, 15456892, 8159759, 17952059, 18077328
Identification Methods two hybrid, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000196 - cell integrity MAPK cascade
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001402 - signal transduction involved in filamentous growth
GO:0001403 - invasive growth in response to glucose limitation
GO:0005524 - ATP binding
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 515
Sc

1 717
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Mm
+ Hs
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025