Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.93 | 1.00 | 0.969 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28205554, 31980649, 22632973, 16280327, 19203586, 11579209, 11956222, 15998322, 17554339, 7891724, 24291004 |
Identification Methods | fluorescent resonance energy transfer, affinity chromatography technology, enzymatic study, in-gel kinase assay, protein kinase assay, coimmunoprecipitation |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PH~PH, PH~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C |
Common GO terms | GO:0001649 - osteoblast differentiation GO:0001893 - maternal placenta development GO:0001938 - positive regulation of endothelial cell proliferation GO:0002042 - cell migration involved in sprouting angiogenesis GO:0002430 - complement receptor mediated signaling pathway and 159 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 11Aug2025