HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: PKH3 (Q03306)
Serine/threonine-protein kinase PKH3 (EC 2.7.11.1) (Pkb-activating kinase homolog 3)
Gene: PKH3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 649 Sc			1 898
+	Sc
		492245 HSP71_YEAST (1-649): 0: 939: 79.35		PKH3_YEAST (1-898): 0: 880: 100.00
+	Hs
		504240 HSP7C_HUMAN (2-649): 0: 946: 72.53		MRCKG_HUMAN (5-798): 5.66e-132: 433: 16.78
+	Hs
		564016 HSP76_HUMAN (4-649): 0: 950: 70.43		AKT1_HUMAN (3-364): 8.2e-138: 421: 24.05
+	Hs
		503528 HSP7C_HUMAN (2-649): 0: 946: 72.53		AKT1_HUMAN (3-364): 8.2e-138: 421: 24.05
+	Hs
		564201 HSP76_HUMAN (4-649): 0: 950: 70.43		KS6B2_HUMAN (4-432): 9.19e-133: 408: 22.22
+	Hs
		504896 HSP7C_HUMAN (2-649): 0: 946: 72.53		KS6B2_HUMAN (4-432): 9.19e-133: 408: 22.22
+	Hs
		871773 HSP72_HUMAN (2-610): 0: 927: 74.63		SIK2_HUMAN (1-773): 3.74e-134: 426: 16.00
+	Sc
		419765 HSP73_YEAST (1-649): 0: 948: 100.00		SNF1_YEAST (7-612): 3.11e-129: 404: 16.96
+	Sc
		419775 HSP72_YEAST (1-649): 0: 941: 78.89		SNF1_YEAST (7-612): 3.11e-129: 404: 16.96
+	Sc
		419774 HSP71_YEAST (1-649): 0: 939: 79.35		SNF1_YEAST (7-612): 3.11e-129: 404: 16.96
+	Sc
		412931 HSP72_YEAST (1-649): 0: 941: 78.89		KAPB_YEAST (1-302): 1.19e-111: 349: 31.60
+	Sc
		412628 HSP72_YEAST (1-649): 0: 941: 78.89		KAPA_YEAST (1-331): 9.18e-110: 345: 28.19
+	Sc
		412627 HSP71_YEAST (1-649): 0: 939: 79.35		KAPA_YEAST (1-331): 9.18e-110: 345: 28.19
+	Hs
		564041 HSP76_HUMAN (4-649): 0: 950: 70.43		KS6A3_HUMAN (11-303): 4.45e-96: 319: 23.67
+	Hs
		503719 HSP7C_HUMAN (2-649): 0: 946: 72.53		KS6A3_HUMAN (11-303): 4.45e-96: 319: 23.67
+	Hs
		182080 HSP76_HUMAN (4-649): 0: 950: 70.43		PDPK1_HUMAN (10-300): 9.59e-67: 234: 43.77
+	Hs
		182076 HSP7C_HUMAN (2-649): 0: 946: 72.53		PDPK1_HUMAN (10-300): 9.59e-67: 234: 43.77
+	Sc
		450168 HSP73_YEAST (1-649): 0: 948: 100.00		PKH1_YEAST (10-300): 1.54e-62: 228: 43.69
+	Sc
		494818 HSP72_YEAST (1-649): 0: 941: 78.89		PKH1_YEAST (10-300): 1.54e-62: 228: 43.69
+	Sc
		492254 HSP71_YEAST (1-649): 0: 939: 79.35		PKH1_YEAST (10-300): 1.54e-62: 228: 43.69