HitPredict

Interactor 1: B2MG (P07151)
Beta-2-microglobulin
Gene: B2m

Interactor 2: HA12 (P16391)
RT1 class I histocompatibility antigen, AA alpha chain
Gene: HA12

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12470953
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set, C1-set~MHC_I
Common GO terms	GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0005615 - extracellular space GO:0009897 - external side of plasma membrane GO:0042605 - peptide antigen binding GO:0042612 - MHC class I protein complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 119 Rn			1 371
+	Hs
		409212 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		HLAA_HUMAN (1-370): 5.02e-170: 480: 69.19
+	Hs
		380213 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HLAH_HUMAN (1-368): 3.88e-155: 442: 64.40
+	Hs
		379830 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		HLAB_HUMAN (1-368): 6.48e-152: 434: 65.49
+	Hs
		379840 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HLAB_HUMAN (1-368): 6.48e-152: 434: 65.49
+	Hs
		379899 HLAF_HUMAN (2-116): 5.69e-49: 160: 21.55		HLAB_HUMAN (1-368): 6.48e-152: 434: 65.49
+	Hs
		409434 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		Q860B5_HUMAN (26-343): 2.16e-148: 423: 66.04
+	Hs
		409232 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		HLAC_HUMAN (1-371): 2.17e-147: 422: 63.34
+	Hs
		520721 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HLAC_HUMAN (1-371): 2.17e-147: 422: 63.34
+	Hs
		409255 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		HLAG_HUMAN (1-315): 1.2e-145: 417: 68.25
+	Hs
		520739 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HLAG_HUMAN (1-315): 1.2e-145: 417: 68.25
+	Hs
		409242 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		HLAE_HUMAN (20-363): 2.21e-138: 399: 62.50
+	Hs
		409280 HLAA_HUMAN (2-116): 3.04e-50: 164: 21.55		HLAF_HUMAN (4-354): 1.71e-137: 397: 62.39
+	Hs
		520732 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HLAE_HUMAN (20-363): 2.21e-138: 399: 62.50
+	Hs
		520757 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HLAF_HUMAN (4-354): 1.71e-137: 397: 62.39
+	Hs
		520882 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		Q6F3D7_HUMAN (26-298): 2.75e-135: 388: 74.36
+	Hs
		520954 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		HMR1_HUMAN (8-356): 5.45e-110: 327: 37.32
+	Hs
		521016 HLAC_HUMAN (2-117): 2.1e-49: 162: 21.37		Q9MY50_HUMAN (1-206): 3.1e-95: 284: 70.39