HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.-) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15383276
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 2000
+	Hs
		437158 K2C8_HUMAN (69-431): 7.94e-131: 391: 36.44		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		474640 VIME_HUMAN (34-402): 6.77e-84: 270: 49.59		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		566367 K2C5_HUMAN (55-403): 3.07e-59: 208: 31.53		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		407282 K2C6B_HUMAN (55-419): 2.72e-59: 207: 30.71		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		876463 K2C6C_HUMAN (55-416): 3.1e-59: 207: 30.96		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		385266 K2C6A_HUMAN (55-419): 1.39e-57: 203: 30.98		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		1088575 KRT84_HUMAN (251-541): 1.98e-09: 62.2: 13.42		CHD3_HUMAN (1-2000): 0: 1804: 100.00
+	Hs
		1007474 KRT83_HUMAN (12-407): 1.19e-85: 275: 29.72		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		474680 VIME_HUMAN (34-402): 6.77e-84: 270: 49.59		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		1132806 K2C73_HUMAN (3-405): 1.75e-82: 268: 30.81		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		1127786 K1H2_HUMAN (8-407): 9.27e-67: 224: 23.69		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		566380 K2C5_HUMAN (55-403): 3.07e-59: 208: 31.53		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		407291 K2C6B_HUMAN (55-419): 2.72e-59: 207: 30.71		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		876470 K2C6C_HUMAN (55-416): 3.1e-59: 207: 30.96		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		385272 K2C6A_HUMAN (55-419): 1.39e-57: 203: 30.98		CHD4_HUMAN (87-1922): 0: 1421: 68.92
+	Hs
		1133001 KRT84_HUMAN (251-541): 1.98e-09: 62.2: 13.42		CHD4_HUMAN (87-1922): 0: 1421: 68.92