HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 520
+	Hs
		453190 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K22E_HUMAN (83-427): 1.05e-121: 372: 55.65
+	Hs
		380541 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		453276 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		KRT83_HUMAN (2-503): 2.84e-103: 320: 40.84
+	Hs
		453418 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C79_HUMAN (9-442): 1.75e-88: 283: 53.14
+	Hs
		380439 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C6B_HUMAN (76-448): 4.72e-80: 262: 59.25
+	Hs
		453213 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C6C_HUMAN (76-448): 1.24e-79: 261: 59.52
+	Hs
		359456 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C6A_HUMAN (76-448): 1.02e-78: 258: 59.79
+	Hs
		453117 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50