Interactor 1: DPOLA (P09884)
DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)
Gene: POLA1

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.680

The method score is based on:

Property Details
Experiments 12641457, 37827155, 24332808, 17666013
Identification Methods pull down, proximity labelling technology, affinity chromatography technology, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006281 - DNA repair
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1462
Hs

1 616
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024