Protein: FES
Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)

Gene: FES
Organism: Homo sapiens
Interactions: 42
UniProt ID: P07332

Gene Ontology (top 5):
GO:0001578 - microtubule bundle formation
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

456088

BCR
Breakpoint cluster region protein

2

20

Small-scale

0.806

High

362604

EGFR
Epidermal growth factor receptor

2

20

High-throughput

0.778

High

456083

HS90A
Heat shock protein HSP 90-alpha

2

20

Small-scale

0.768

High

456089

EZRI
Ezrin

1

20

Small-scale

0.766

High

456082

FES
Tyrosine-protein kinase Fes/Fps

2

20

Small-scale

0.755

High

456115

HSH2D
Hematopoietic SH2 domain-containing protein

1

20

Small-scale

0.740

High

456085

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

456087

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

456105

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.692

High

456106

PLEC
Plectin

1

14

High-throughput

0.691

High

410524

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

456092

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

456101

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

19

Small-scale

0.647

High

456104

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

19

Small-scale

0.647

High

456108

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

456112

ABI1
Abl interactor 1

1

20

Small-scale

0.647

High

456117

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

17

Small-scale

0.647

High

456090

DESP
Desmoplakin

2

17

High-throughput

0.621

High

456084

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

456093

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

456096

STAT3
Signal transducer and activator of transcription 3

1

18

Small-scale

0.618

High

456100

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.573

High

456116

MDFI
MyoD family inhibitor

1

0

High-throughput

0.536

High

456086

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

456111

FBX50
F-box only protein 50

1

1

High-throughput

0.536

High

456103

TIF1B
Transcription intermediary factor 1-beta

1

9

Small-scale

0.535

High

456109

MYOME
Myomegalin

1

14

High-throughput

0.508

High

456110

ZN746
Zinc finger protein 746

1

2

High-throughput

0.508

High

421314

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

456095

HSP74
Heat shock 70 kDa protein 4

1

20

Small-scale

0.501

High

456098

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

17

High-throughput

0.501

High

456102

PPID
Peptidyl-prolyl cis-trans isomerase D

1

4

Small-scale

0.501

High

456107

TEBP
Prostaglandin E synthase 3

1

1

Small-scale

0.501

High

456119

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.493

High

456099

TXTP
Tricarboxylate transport protein, mitochondrial

1

7

High-throughput

0.489

High

456113

POF1B
Protein POF1B

1

1

High-throughput

0.489

High

456114

ZN775
Zinc finger protein 775

1

4

High-throughput

0.464

High

456097

NSF
Vesicle-fusing ATPase

1

3

Small-scale

0.445

High

456091

SPI1
Transcription factor PU.1

1

4

Small-scale

0.437

High

456094

ELF1
ETS-related transcription factor Elf-1

1

5

Small-scale

0.437

High

456118

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.288

High


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Last updated: 11Aug2025