HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	15324660
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 245
+	Hs
		990190 TBB3_HUMAN (1-444): 0: 712: 92.57		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Bt
		990078 TBB5_BOVIN (1-429): 0: 709: 100.00		1433Z_BOVIN (1-245): 1.67e-144: 405: 100.00
+	Hs
		457351 TBB5_HUMAN (1-429): 0: 709: 100.00		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Mm
		989996 TBB2A_MOUSE (1-430): 0: 704: 96.98		1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59
+	Hs
		971396 TBB4B_HUMAN (1-427): 0: 707: 98.36		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		971947 TBB2B_HUMAN (1-430): 0: 707: 97.44		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		990205 TBB2A_HUMAN (1-430): 0: 704: 96.98		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		690981 TBB3_HUMAN (1-444): 0: 712: 92.57		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		457242 TBB5_HUMAN (1-429): 0: 709: 100.00		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		457256 TBB5_HUMAN (1-429): 0: 709: 100.00		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		690894 TBB4B_HUMAN (1-427): 0: 707: 98.36		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		690990 TBB2A_HUMAN (1-430): 0: 704: 96.98		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Zm
		80522 B4FTM1_MAIZE (1-430): 0: 697: 86.98		K7U5A5_MAIZE (3-239): 5.24e-139: 392: 62.86
+	Rn
		64504 A6KQR9_RAT (1-427): 0: 702: 97.42		1433B_RAT (1-242): 2.01e-128: 364: 86.78
+	Hs
		1049265 TBB3_HUMAN (1-444): 0: 712: 92.57		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		457348 TBB5_HUMAN (1-429): 0: 709: 100.00		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59