HitPredict

Interactor 1: ROA1 (P07909)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A)
Gene: Hrb98DE

Interactor 2: Q9W1I0 (Q9W1I0)
TAR DNA-binding protein 43
Gene: TBPH

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	24492607
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0033119 - negative regulation of RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Dm			1 332
+	Dm
		877843 RB87F_DROME (8-203): 5.73e-79: 248: 74.49		Q9W1I0_DROME (1-332): 4.84e-86: 263: 100.00
+	Hs
		909509 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		ROA3_HUMAN (100-268): 8.6e-73: 231: 30.39
+	Hs
		909571 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		HNRPD_HUMAN (81-310): 4.99e-72: 228: 24.37
+	Hs
		214288 MSI1H_HUMAN (13-352): 5.08e-60: 199: 24.15		TADBP_HUMAN (2-310): 2.31e-66: 216: 52.09
+	Hs
		909553 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		TADBP_HUMAN (2-310): 2.31e-66: 216: 52.09
+	Hs
		214259 MSI1H_HUMAN (13-352): 5.08e-60: 199: 24.15		MSI1H_HUMAN (91-319): 5.18e-56: 187: 23.85
+	Mm
		1222783 MSI1H_MOUSE (13-352): 1.23e-59: 198: 24.15		MSI1H_MOUSE (91-319): 1.99e-55: 186: 23.85
+	Hs
		214326 MSI1H_HUMAN (13-352): 5.08e-60: 199: 24.15		MSI2H_HUMAN (88-311): 2.57e-53: 179: 22.22
+	Dm
		877795 RB87F_DROME (8-203): 5.73e-79: 248: 74.49		RB27C_DROME (109-306): 3.71e-18: 86.7: 32.42
+	Dm
		877827 RB87F_DROME (8-203): 5.73e-79: 248: 74.49		SQD_DROME (86-266): 4.24e-17: 82.8: 31.92
+	Sc
		403721 HRP1_YEAST (16-365): 1.62e-55: 191: 25.71		PABP_YEAST (85-282): 2.67e-34: 133: 16.43
+	Hs
		485006 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		ROA1_HUMAN (80-186): 4.96e-28: 113: 31.48
+	Hs
		909593 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		RA1L2_HUMAN (80-192): 1.3e-27: 111: 28.95
+	Hs
		485135 HNRPD_HUMAN (2-304): 4.73e-54: 183: 30.03		ROA1_HUMAN (80-186): 4.96e-28: 113: 31.48
+	Mm
		881002 HNRPD_MOUSE (2-304): 4.03e-54: 183: 29.70		ROA1_MOUSE (80-186): 4.68e-28: 112: 31.48
+	Dm
		877797 RB97D_DROME (18-208): 3.65e-62: 207: 59.28		RB27C_DROME (109-306): 3.71e-18: 86.7: 32.42
+	Hs
		650657 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		ROA2_HUMAN (174-270): 8.88e-19: 87.7: 24.27
+	Hs
		650751 HNRPD_HUMAN (2-304): 4.73e-54: 183: 30.03		ROA2_HUMAN (174-270): 8.88e-19: 87.7: 24.27
+	Hs
		550189 ROA3_HUMAN (23-205): 6.28e-57: 191: 59.02		PABP1_HUMAN (182-270): 6.44e-10: 62.1: 18.75
+	Hs
		550278 HNRPD_HUMAN (2-304): 4.73e-54: 183: 30.03		PABP1_HUMAN (182-270): 6.44e-10: 62.1: 18.75