HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31586073, 31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0000281 - mitotic cytokinesis GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1124
+	Hs
		962526 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		955639 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		978330 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		870522 RHO1_DROME (1-193): 9.94e-77: 229: 85.49		ANLN_DROME (542-1112): 1.61e-160: 511: 29.84
+	Ce
		110139 G5EBV3_CAEEL (2-193): 4.53e-79: 235: 50.52		ANI1_CAEEL (376-1113): 3.33e-131: 430: 19.24
+	Rn
		962877 RHOA_RAT (1-193): 1.03e-81: 242: 92.23		RTKN_RAT (718-1113): 4.13e-121: 385: 17.31
+	Mm
		1298097 RHOA_MOUSE (1-193): 1.03e-81: 242: 92.23		RTKN_MOUSE (721-1113): 1.31e-118: 379: 17.43
+	Hs
		962429 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		RTKN_HUMAN (721-1113): 5.12e-119: 380: 16.71
+	Hs
		988661 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		RTKN_HUMAN (721-1113): 5.12e-119: 380: 16.71
+	Hs
		466435 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		RTKN_HUMAN (721-1113): 5.12e-119: 380: 16.71
+	Hs
		466350 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		RTKN2_HUMAN (724-1113): 1.09e-112: 365: 18.23
+	Hs
		978259 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		RTKN_HUMAN (721-1113): 5.12e-119: 380: 16.71
+	Hs
		978150 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		RTKN2_HUMAN (724-1113): 1.09e-112: 365: 18.23