Interactor 1: ODPA (P08559)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: PDHA1

Interactor 2: ODPA (P08559)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: PDHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~E1_dh
Common GO terms GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 390
Hs

1 390
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ At
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Ec

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Last updated: 11Aug2025