Interactor 1: ODO1 (Q60597)
2-oxoglutarate dehydrogenase complex component E1 (E1o) (OGDC-E1) (OGDH-E1) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Alpha-KGDH-E1) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase)
Gene: Ogdh

Interactor 2: ODO1 (Q60597)
2-oxoglutarate dehydrogenase complex component E1 (E1o) (OGDC-E1) (OGDH-E1) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Alpha-KGDH-E1) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase)
Gene: Ogdh

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-oxogl_dehyd_N~E1_dh, E1_dh~E1_dh, E1_dh~OxoGdeHyase_C, E1_dh~Transket_pyr, OxoGdeHyase_C~OxoGdeHyase_C, OxoGdeHyase_C~Transket_pyr, Transket_pyr~Transket_pyr
Common GO terms GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0006091 - generation of precursor metabolites and energy
GO:0006096 - glycolytic process
and 16 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1023
Mm

1 1023
+ Hs
+ Mm
+ Mm
+ Sc
+ Ec
+ Hs
+ Sc
+ Hs
+ Mm
+ At
+ Mm
+ Hs
+ Mm

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Last updated: 11Aug2025