HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 746
+	Hs
		478065 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		EZH2_HUMAN (1-746): 0: 864: 100.00
+	Hs
		250630 HNRPQ_HUMAN (4-224): 8.47e-14: 71.6: 20.00		EZH2_HUMAN (1-746): 0: 864: 100.00
+	Hs
		1101972 PABP4_HUMAN (148-225): 2e-13: 70.5: 19.28		EZH2_HUMAN (1-746): 0: 864: 100.00
+	Hs
		550304 PABP1_HUMAN (141-225): 2.64e-13: 70.1: 17.78		EZH2_HUMAN (1-746): 0: 864: 100.00
+	Hs
		1028992 TIAR_HUMAN (143-223): 1.61e-10: 61.7: 26.19		EZH2_HUMAN (1-746): 0: 864: 100.00
+	Hs
		478197 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		SETD2_HUMAN (190-732): 1.93e-89: 310: 16.64
+	Hs
		550417 PABP1_HUMAN (141-225): 2.64e-13: 70.1: 17.78		NSD1_HUMAN (275-729): 2.84e-90: 312: 15.82
+	Sc
		863940 NAM8_YEAST (1-224): 6.19e-42: 150: 16.09		SET2_YEAST (470-733): 1.19e-59: 216: 25.56
+	Hs
		250898 HNRPQ_HUMAN (4-224): 8.47e-14: 71.6: 20.00		SET1B_HUMAN (619-732): 1.39e-18: 93.2: 40.52