HitPredict

Interactor 1: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 411
+	Hs
		474174 NFIC_HUMAN (1-508): 1.62e-162: 472: 100.00		DDX17_HUMAN (14-411): 7.29e-132: 397: 30.79
+	Hs
		807423 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		IF4A3_HUMAN (1-411): 1.51e-142: 413: 100.00
+	Hs
		1133574 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		DDX17_HUMAN (14-411): 7.29e-132: 397: 30.79
+	Hs
		1087911 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		DDX17_HUMAN (14-411): 7.29e-132: 397: 30.79
+	Hs
		142875 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		IF4A3_HUMAN (1-411): 1.51e-142: 413: 100.00
+	Hs
		143160 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		DDX17_HUMAN (14-411): 7.29e-132: 397: 30.79
+	Hs
		473795 NFIC_HUMAN (1-508): 1.62e-162: 472: 100.00		DDX6_HUMAN (35-407): 1.16e-88: 278: 37.83
+	Hs
		684241 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		DDX6_HUMAN (35-407): 1.16e-88: 278: 37.83
+	Hs
		684213 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		DDX6_HUMAN (35-407): 1.16e-88: 278: 37.83
+	Hs
		142841 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		DDX6_HUMAN (35-407): 1.16e-88: 278: 37.83
+	Sc
		808372 SEC31_YEAST (184-421): 1.2e-09: 63: 11.89		DHH1_YEAST (39-408): 1.29e-169: 486: 40.54
+	Hs
		608455 RPB1_HUMAN (374-496): 2.4e-09: 62.2: 20.33		DDX5_HUMAN (25-411): 9.7e-134: 398: 30.63
+	Hs
		667389 RPB1_HUMAN (374-496): 2.4e-09: 62.2: 20.33		DDX17_HUMAN (14-411): 7.29e-132: 397: 30.79
+	Mm
		476226 RPB1_MOUSE (375-496): 7.88e-09: 60.7: 19.67		DDX5_MOUSE (25-411): 8.71e-134: 398: 30.63
+	Sc
		666458 SEC31_YEAST (184-421): 1.2e-09: 63: 11.89		DBP2_YEAST (4-409): 1.37e-133: 395: 32.37
+	Hs
		193086 RPB1_HUMAN (374-496): 2.4e-09: 62.2: 20.33		DDX3Y_HUMAN (17-410): 1.04e-128: 387: 32.45