HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: OTU7B (Q6GQQ9)
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)
Gene: OTUD7B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.759

Property	Details
Experiments	18029035, 32814053
Identification Methods	pull down, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	OTU~ubiquitin, UBA_4~ubiquitin, ubiquitin~zf-A20
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 843
+	Mm
		70741 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		OTU7B_MOUSE (1-843): 0: 1362: 91.00
+	Hs
		475915 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		OTU7B_HUMAN (1-843): 0: 1384: 100.00
+	Hs
		476093 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		OTU7A_HUMAN (1-823): 0: 1135: 54.56
+	Hs
		474920 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		TNAP3_HUMAN (130-842): 5.32e-100: 330: 24.17
+	Dm
		1367032 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		TRBID_DROME (142-393): 2.74e-85: 290: 29.62
+	Dr
		48762 F1QHN6_DANRE (1-228): 3.12e-92: 282: 100.00		ZRN1B_DANRE (129-392): 1.22e-84: 287: 31.31
+	Mm
		476820 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		TNAP3_MOUSE (130-494): 2.81e-99: 327: 32.84
+	Hs
		475332 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TNAP3_HUMAN (130-842): 5.32e-100: 330: 24.17
+	Mm
		476855 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		ZRAN1_MOUSE (132-392): 1.45e-88: 297: 32.29
+	Hs
		476517 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		ZRAN1_HUMAN (132-392): 2.26e-88: 297: 32.29
+	Hs
		924207 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		ZRAN1_HUMAN (132-392): 2.26e-88: 297: 32.29