Protein: MYO10
Unconventional myosin-X (Unconventional myosin-10)

Gene: MYO10
Organism: Homo sapiens
Interactions: 145
UniProt ID: Q9HD67

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0001726 - ruffle
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1439696

FBW1B
F-box/WD repeat-containing protein 11

3

5

High-throughput

0.839

High

993339

ACTG
Actin, cytoplasmic 2

3

16

High-throughput

0.827

High

1439699

FBW1A
F-box/WD repeat-containing protein 1A

2

4

High-throughput

0.811

High

299581

TRIO
Triple functional domain protein

2

16

Small-scale

0.754

High

953118

ACTB
Actin, cytoplasmic 1

2

16

High-throughput

0.754

High

1258043

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

1

4

Small-scale

0.747

High

692812

CALL3
Calmodulin-like protein 3

2

9

Small-scale

0.706

High

835759

KPCI
Protein kinase C iota type

1

6

High-throughput

0.691

High

1243052

PKN3
Serine/threonine-protein kinase N3

1

6

High-throughput

0.691

High

1392670

MYO19
Unconventional myosin-XIX

1

19

High-throughput

0.691

High

1418677

PAR6B
Partitioning defective 6 homolog beta

1

2

High-throughput

0.691

High

915191

CAZA1
F-actin-capping protein subunit alpha-1

3

8

High-throughput

0.640

High

136003

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

7

Small-scale

0.618

High

159873

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

5

High-throughput

0.618

High

179250

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

6

Small-scale

0.618

High

443528

CDK1
Cyclin-dependent kinase 1

1

11

Small-scale

0.618

High

767503

RADI
Radixin

1

8

Small-scale

0.618

High

897984

CDK9
Cyclin-dependent kinase 9

1

18

Small-scale

0.618

High

920290

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.618

High

953688

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

Small-scale

0.618

High

958355

ARP2
Actin-related protein 2

1

18

Small-scale

0.618

High

1066503

RBBP4
Histone-binding protein RBBP4

1

2

Small-scale

0.618

High

1110411

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

2

Small-scale

0.618

High

1110569

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

2

Small-scale

0.618

High

1116031

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

19

High-throughput

0.618

High

1420063

KPCD2
Serine/threonine-protein kinase D2

1

13

High-throughput

0.618

High

1439685

MYO10
Unconventional myosin-X

1

18

Small-scale

0.618

High

1439686

ANLN
Anillin

1

7

High-throughput

0.618

High

1395082

JPH4
Junctophilin-4

2

0

High-throughput

0.602

High

845994

DCC
Netrin receptor DCC

1

4

Small-scale

0.589

High

1015127

ARF5
ADP-ribosylation factor 5

1

0

Small-scale

0.586

High

612121

ITB5
Integrin beta-5

1

6

Small-scale

0.561

High

1007786

RAE1L
mRNA export factor RAE1

1

2

Small-scale

0.553

High

1291227

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

1383480

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

14

High-throughput

0.536

High

1439691

KLH14
Kelch-like protein 14

1

5

High-throughput

0.536

High

573682

ENPL
Endoplasmin

1

10

High-throughput

0.515

High

1439693

MIOX
Inositol oxygenase

1

0

High-throughput

0.513

High

1219349

ECM29
Proteasome adapter and scaffold protein ECM29

1

8

Small-scale

0.504

High

1259520

TBA1A
Tubulin alpha-1A chain

1

2

Small-scale

0.501

High

1348967

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

143704

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

12

Small-scale

0.479

High

173403

XPO1
Exportin-1

1

2

High-throughput

0.479

High

175219

SC16A
Protein transport protein Sec16A

1

4

Small-scale

0.479

High

179401

ARPC2
Actin-related protein 2/3 complex subunit 2

1

3

Small-scale

0.479

High

208572

PJA2
E3 ubiquitin-protein ligase Praja-2

1

5

Small-scale

0.479

High

274767

DNJB6
DnaJ homolog subfamily B member 6

1

1

Small-scale

0.479

High

288026

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

Small-scale

0.479

High

323914

SC31A
Protein transport protein Sec31A

1

2

Small-scale

0.479

High

504764

FBSP1
F-box/SPRY domain-containing protein 1

1

12

Small-scale

0.479

High

562652

RINI
Ribonuclease inhibitor

1

8

Small-scale

0.479

High

679264

DNJB1
DnaJ homolog subfamily B member 1

1

2

Small-scale

0.479

High

687518

PTBP1
Polypyrimidine tract-binding protein 1

1

3

High-throughput

0.479

High

728974

PUR9
Bifunctional purine biosynthesis protein ATIC

1

2

Small-scale

0.479

High

774115

ADDA
Alpha-adducin

1

3

Small-scale

0.479

High

800113

COIL
Coilin

1

1

Small-scale

0.479

High

831469

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

840605

DPP6
A-type potassium channel modulatory protein DPP6

1

1

Small-scale

0.479

High

848179

MAGA1
Melanoma-associated antigen 1

1

11

Small-scale

0.479

High

854746

RAGP1
Ran GTPase-activating protein 1

1

3

Small-scale

0.479

High

874199

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

1

Small-scale

0.479

High

904133

BAP31
B-cell receptor-associated protein 31

1

10

Small-scale

0.479

High

933737

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

3

Small-scale

0.479

High

947335

NAL11
NACHT, LRR and PYD domains-containing protein 11

1

3

High-throughput

0.479

High

986229

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

991720

DYL1
Dynein light chain 1, cytoplasmic

1

2

Small-scale

0.479

High

994386

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

12

Small-scale

0.479

High

997147

TBA4A
Tubulin alpha-4A chain

1

3

Small-scale

0.479

High

1007543

KRT85
Keratin, type II cuticular Hb5

1

3

Small-scale

0.479

High

1090934

TRAF2
TNF receptor-associated factor 2

1

12

Small-scale

0.479

High

1102106

PABP4
Polyadenylate-binding protein 4

1

1

High-throughput

0.479

High

1105663

GOGA4
Golgin subfamily A member 4

1

18

Small-scale

0.479

High

1112995

CUL2
Cullin-2

1

8

Small-scale

0.479

High

1114365

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1120060

COTL1
Coactosin-like protein

1

4

Small-scale

0.479

High

1127828

KRT81
Keratin, type II cuticular Hb1

1

3

Small-scale

0.479

High

1134543

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

3

Small-scale

0.479

High

1138079

TNIP1
TNFAIP3-interacting protein 1

1

18

High-throughput

0.479

High

1141953

EEA1
Early endosome antigen 1

1

19

High-throughput

0.479

High

1143981

IPYR
Inorganic pyrophosphatase

1

1

Small-scale

0.479

High

1152257

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

Small-scale

0.479

High

1197569

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

10

High-throughput

0.479

High

1204806

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

4

Small-scale

0.479

High

1208895

H2B2F
Histone H2B type 2-F

1

13

Small-scale

0.479

High

1212858

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

Small-scale

0.479

High

1273945

K2C74
Keratin, type II cytoskeletal 74

1

4

Small-scale

0.479

High

1331363

ENAH
Protein enabled homolog

1

7

Small-scale

0.479

High

1365765

GCN1
Stalled ribosome sensor GCN1

1

8

Small-scale

0.479

High

1371545

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

10

Small-scale

0.479

High

1371710

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

12

Small-scale

0.479

High

1381095

HDA10
Polyamine deacetylase HDAC10

1

16

Small-scale

0.479

High

1394525

PAWR
PRKC apoptosis WT1 regulator protein

1

1

Small-scale

0.479

High

1410279

KLDC3
Kelch domain-containing protein 3

1

14

Small-scale

0.479

High

1416743

OSB10
Oxysterol-binding protein-related protein 10

1

1

Small-scale

0.479

High

1439692

HDAC6
Protein deacetylase HDAC6

1

16

High-throughput

0.479

High

1439694

TES
Testin

1

4

High-throughput

0.479

High

1439695

NGAP
Ras GTPase-activating protein nGAP

1

10

Small-scale

0.479

High

1439697

FZR1
Fizzy-related protein homolog

1

6

High-throughput

0.479

High

1439698

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

Small-scale

0.479

High

1439700

TR150
Thyroid hormone receptor-associated protein 3

1

5

Small-scale

0.479

High

1439701

MAGD1
Melanoma-associated antigen D1

1

10

Small-scale

0.479

High

1437653

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

1

0

Small-scale

0.460

High

1439687

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

64129

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

Small-scale

0.458

High

128326

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

Small-scale

0.458

High

253113

PLIN3
Perilipin-3

1

0

Small-scale

0.458

High

347351

BAG2
BAG family molecular chaperone regulator 2

1

0

Small-scale

0.458

High

549692

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

Small-scale

0.458

High

821812

NNMT
Nicotinamide N-methyltransferase

1

0

Small-scale

0.458

High

912609

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

Small-scale

0.458

High

1120596

IL18
Interleukin-18

1

0

Small-scale

0.458

High

1161066

FSCN1
Fascin

1

0

Small-scale

0.458

High

1164206

UGPA
UTP--glucose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

1239948

CAVN1
Caveolae-associated protein 1

1

0

Small-scale

0.458

High

1293335

EZHIP
EZH inhibitory protein

1

0

Small-scale

0.458

High

1390358

I17RA
Interleukin-17 receptor A

1

0

Small-scale

0.458

High

1415120

TBB2B
Tubulin beta-2B chain

1

1

Small-scale

0.457

High

765909

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.445

High

1133807

SL9A5
Sodium/hydrogen exchanger 5

1

1

High-throughput

0.445

High

1431943

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

1

High-throughput

0.445

High

229821

CALU
Calumenin

1

2

Small-scale

0.437

High

254473

MAGC1
Melanoma-associated antigen C1

1

11

Small-scale

0.437

High

637159

CSRP1
Cysteine and glycine-rich protein 1

1

10

Small-scale

0.437

High

813494

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

5

Small-scale

0.437

High

881101

NASP
Nuclear autoantigenic sperm protein

1

3

Small-scale

0.437

High

1118607

TBB2A
Tubulin beta-2A chain

1

1

Small-scale

0.437

High

1149998

TERF2
Telomeric repeat-binding factor 2

1

3

High-throughput

0.437

High

1255642

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

1335606

SPRY3
SPRY domain-containing protein 3

1

8

Small-scale

0.437

High

1339853

PJA1
E3 ubiquitin-protein ligase Praja-1

1

5

Small-scale

0.437

High

1394957

MAGD4
Melanoma-associated antigen D4

1

11

Small-scale

0.437

High

1439689

BCLF1
Bcl-2-associated transcription factor 1

1

7

Small-scale

0.437

High

190490

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.426

High

906354

GPC3
Glypican-3

1

0

High-throughput

0.426

High

1439688

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.251

Low

292030

CRTAP
Cartilage-associated protein

1

0

Small-scale

0.249

Low

734009

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

Small-scale

0.249

Low

1009820

MT1X
Metallothionein-1X

1

0

Small-scale

0.249

Low

1038948

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

0

Small-scale

0.249

Low

1131401

GANAB
Neutral alpha-glucosidase AB

1

0

Small-scale

0.249

Low

1271151

TM10C
tRNA methyltransferase 10 homolog C

1

0

Small-scale

0.249

Low

1409604

NIPS1
Protein NipSnap homolog 1

1

0

Small-scale

0.249

Low

1439690

SACS
Sacsin

1

0

Small-scale

0.249

Low

192135

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025