Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 17525341, 27977889, 17349954
Identification Methods pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~zf-C3HC4
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0016567 - protein ubiquitination
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 685
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024