HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	34642328, 33576509, 12834344
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 147
+	Hs
		475817 UBC_HUMAN (1-685): 0: 846: 100.00		UB2V2_HUMAN (4-147): 8.54e-72: 213: 88.89
+	Hs
		476604 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44
+	Hs
		475501 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27
+	Hs
		135917 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2C_HUMAN (2-147): 2.51e-56: 175: 25.17
+	Hs
		475586 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D2_HUMAN (12-146): 1.25e-56: 175: 22.96
+	Hs
		475485 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2A_HUMAN (9-146): 1.66e-56: 174: 22.46
+	Hs
		475550 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D3_HUMAN (12-146): 3.82e-56: 173: 22.96
+	Hs
		475597 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2B_HUMAN (9-146): 8.36e-56: 173: 21.74
+	Hs
		476155 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E3_HUMAN (1-145): 1.38e-54: 172: 22.76
+	Hs
		476218 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E2_HUMAN (2-145): 1.8e-54: 171: 23.61
+	Xl
		919927 Q7SY79_XENLA (77-685): 0: 744: 99.84		UB2D2_XENLA (12-146): 1.25e-56: 175: 22.96
+	Hs
		475504 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E1_HUMAN (7-124): 1.45e-12: 63.8: 29.37
+	Dm
		639414 Q9W418_DROME (229-685): 0: 557: 99.78		UBCD1_DROME (12-146): 1.76e-56: 174: 24.44
+	Sc
		477383 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		MMS2_YEAST (10-145): 1.52e-61: 187: 50.00
+	Sc
		410203 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC2_YEAST (9-147): 8.37e-55: 171: 20.14
+	Sc
		477103 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC4_YEAST (11-146): 3.6e-55: 171: 21.32
+	At
		715116 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC8_ARATH (12-146): 1.2e-57: 177: 23.70
+	At
		715132 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC9_ARATH (12-146): 1.76e-57: 177: 23.70
+	At
		715147 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC10_ARATH (12-146): 1.55e-57: 177: 23.70
+	At
		639385 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC1_ARATH (9-146): 2.27e-56: 174: 19.42