HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBE2Z (Q9H832)
Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
Gene: UBE2Z

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27182664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 354
+	Hs
		476431 UBC_HUMAN (1-685): 0: 846: 100.00		BIRC6_HUMAN (87-353): 1.31e-68: 235: 29.62
+	Hs
		476604 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D4_HUMAN (99-253): 1.41e-72: 223: 33.12
+	Hs
		475586 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D2_HUMAN (99-253): 3.54e-72: 222: 34.40
+	Hs
		475501 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D1_HUMAN (99-253): 2.91e-71: 220: 31.85
+	Hs
		475550 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D3_HUMAN (99-253): 7.74e-71: 219: 34.40
+	Hs
		476218 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E2_HUMAN (44-253): 2.74e-65: 207: 24.53
+	Hs
		476155 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E3_HUMAN (74-253): 5.35e-65: 206: 27.47
+	Hs
		475504 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E1_HUMAN (82-253): 6.89e-65: 205: 27.01
+	Hs
		476424 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2T_HUMAN (99-291): 1.1e-61: 197: 27.14
+	Hs
		475483 UBC_HUMAN (1-685): 0: 846: 100.00		UB2R1_HUMAN (96-283): 9.14e-57: 186: 26.36
+	Xl
		919927 Q7SY79_XENLA (77-685): 0: 744: 99.84		UB2D2_XENLA (99-253): 3.54e-72: 222: 34.40
+	Hs
		476332 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2O_HUMAN (104-242): 7.06e-21: 96.3: 40.14
+	Hs
		475552 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2N_HUMAN (103-226): 3.77e-18: 82: 36.29
+	Dm
		639414 Q9W418_DROME (229-685): 0: 557: 99.78		UBCD1_DROME (99-253): 8.72e-71: 219: 34.40
+	Sc
		477103 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC4_YEAST (99-253): 3.84e-68: 212: 31.85
+	At
		715116 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC8_ARATH (99-253): 8.5e-69: 214: 35.67
+	At
		715132 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC9_ARATH (99-253): 1.02e-68: 213: 36.31
+	At
		715147 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC10_ARATH (99-253): 2.36e-68: 213: 35.67
+	At
		715157 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC11_ARATH (99-253): 7.12e-68: 212: 35.03
+	At
		639385 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC1_ARATH (102-246): 1.9e-56: 182: 31.97