HitPredict

Interactor 1: TBB3 (P08841)
Tubulin beta-3 chain (Beta-3-tubulin)
Gene: betaTub60D

Interactor 2: IKKB (Q9VEZ5)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappaB kinase subunit beta) (EC 2.7.11.10) (Cactus kinase IKK) (IKK-like protein) (Immune response deficient protein 5) (Lipopolysaccharide-activated kinase) (DLAK)
Gene: IKKbeta

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23749869
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Dm			1 751
+	Dm
		1174609 TBB1_DROME (1-435): 0: 700: 91.72		IKKB_DROME (1-751): 0: 631: 100.00
+	Dm
		963929 TBB2_DROME (1-436): 0: 691: 89.45		IKKB_DROME (1-751): 0: 631: 100.00
+	Hs
		168685 TBB3_HUMAN (1-451): 0: 703: 88.50		CSKP_HUMAN (39-703): 5.99e-121: 386: 17.12
+	Mm
		267269 TBB5_MOUSE (1-435): 0: 703: 90.81		CSKP_MOUSE (39-703): 5.81e-121: 386: 17.12
+	Hs
		167791 TBB5_HUMAN (1-435): 0: 703: 90.81		IKKB_HUMAN (30-693): 1.19e-116: 371: 22.27
+	Hs
		167967 TBB2B_HUMAN (1-436): 0: 701: 90.37		IKKB_HUMAN (30-693): 1.19e-116: 371: 22.27
+	Hs
		167786 TBB4A_HUMAN (1-433): 0: 697: 90.30		IKKB_HUMAN (30-693): 1.19e-116: 371: 22.27
+	Hs
		457433 TBB5_HUMAN (1-435): 0: 703: 90.81		IKKE_HUMAN (35-458): 2.82e-105: 339: 26.73
+	Hs
		408064 TBB4A_HUMAN (1-433): 0: 697: 90.30		IKKE_HUMAN (35-458): 2.82e-105: 339: 26.73
+	Hs
		177767 TBB5_HUMAN (1-435): 0: 703: 90.81		IKKA_HUMAN (39-400): 5.09e-100: 326: 30.77
+	Hs
		177762 TBB4A_HUMAN (1-433): 0: 697: 90.30		IKKA_HUMAN (39-400): 5.09e-100: 326: 30.77
+	Hs
		457756 TBB5_HUMAN (1-435): 0: 703: 90.81		TBK1_HUMAN (35-461): 4.91e-83: 281: 24.44
+	Hs
		408187 TBB4A_HUMAN (1-433): 0: 697: 90.30		TBK1_HUMAN (35-461): 4.91e-83: 281: 24.44
+	Hs
		457255 TBB5_HUMAN (1-435): 0: 703: 90.81		AKT1_HUMAN (26-344): 1.12e-81: 270: 24.18
+	Hs
		728160 TBB4B_HUMAN (1-433): 0: 702: 91.22		AKT1_HUMAN (26-344): 1.12e-81: 270: 24.18
+	Hs
		457676 TBB5_HUMAN (1-435): 0: 703: 90.81		KPCD2_HUMAN (47-319): 1.83e-21: 102: 32.27
+	Hs
		457405 TBB5_HUMAN (1-435): 0: 703: 90.81		PAK1_HUMAN (41-288): 3.17e-21: 100: 30.59
+	Hs
		997308 TBB4B_HUMAN (1-433): 0: 702: 91.22		PAK1_HUMAN (41-288): 3.17e-21: 100: 30.59
+	Hs
		1096493 TBB2B_HUMAN (1-436): 0: 701: 90.37		PAK1_HUMAN (41-288): 3.17e-21: 100: 30.59
+	Hs
		1096492 TBB6_HUMAN (1-438): 0: 696: 88.36		PAK1_HUMAN (41-288): 3.17e-21: 100: 30.59