HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: ITSN2 (Q9NZM3)
Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)
Gene: ITSN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	28190767, 38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, SH3_9~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1697
+	Hs
		475816 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		475982 UBC_HUMAN (1-685): 0: 846: 100.00		FGD2_HUMAN (1173-1587): 2.78e-78: 275: 22.90
+	Mm
		70590 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		B2RR82_MOUSE (1-1697): 0: 928: 90.56
+	Hs
		476502 UBC_HUMAN (1-685): 0: 846: 100.00		EP15R_HUMAN (3-509): 1.83e-36: 152: 16.67
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (2-1693): 0: 861: 56.37
+	Hs
		475452 UBC_HUMAN (1-685): 0: 846: 100.00		EPS15_HUMAN (7-478): 5.01e-32: 138: 16.98
+	Rn
		1126748 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q5JC29_RAT (7-410): 1.28e-31: 136: 18.55
+	Mm
		476700 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPS15_MOUSE (7-405): 5.97e-31: 134: 17.56
+	Hs
		924030 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		ARHGG_HUMAN (1196-1469): 3.19e-21: 102: 30.27
+	Hs
		924052 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		ARHG8_HUMAN (1196-1542): 4.68e-20: 98.6: 26.02
+	Rn
		102529 UBC_RAT (1-108): 1.27e-29: 127: 90.74		G3V856_RAT (1200-1461): 1.08e-21: 103: 30.04
+	Mm
		476822 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EP15R_MOUSE (13-132): 1.69e-16: 87.7: 27.87
+	Rn
		88639 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZJR1_RAT (429-618): 3.1e-11: 70.6: 16.32