Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: GRPE (P38523)
GrpE protein homolog, mitochondrial
Gene: MGE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 11564892, 37968396, 23345595, 23864706, 11601843, 11273703, 10196216, 8166717, 9048947, 9367739, 7935381, 9155010, 8524277, 8168496, 25792736, 15719019, 24829379, 32051233, 20007714, 19036727 and 2 others

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Identification Methods affinity chromatography technology, pull down, biochemical, cross-linking study, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains GrpE~HSP70
Common GO terms GO:0001405 - PAM complex, Tim23 associated import motor
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
GO:0006886 - intracellular protein transport
and 3 others

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Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 654
Sc

1 228
+ Sc
+ Rn
+ Hs
+ Sc
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024