HitPredict

Interactor 1: PDIA1 (P09103)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Endoplasmic reticulum resident protein 59) (ER protein 59) (ERp59) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4hb

Interactor 2: PDIA1 (P09103)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Endoplasmic reticulum resident protein 59) (ER protein 59) (ERp59) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4hb

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29222160
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6, Thioredoxin_6~Thioredoxin_6
Common GO terms GO:0003756 - protein disulfide isomerase activity
GO:0003779 - actin binding
GO:0004656 - procollagen-proline 4-dioxygenase activity
GO:0005178 - integrin binding
GO:0005783 - endoplasmic reticulum
and 23 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 509
Mm

1 509
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Sc
+ Mm
+ Sc
+ Hs
+ Dm
+ Dm
+ Dm
+ Nc
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025