Interactor 1: PDI (P54399)
Protein disulfide-isomerase (PDI) (dPDI) (EC 5.3.4.1)
Gene: PDI

Interactor 2: Q3YMU0 (Q3YMU0)
Protein disulfide-isomerase (EC 5.3.4.1)
Gene: ERp60

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6, Thioredoxin_6~Thioredoxin_6
Common GO terms GO:0003756 - protein disulfide isomerase activity
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006457 - protein folding
GO:0012505 - endomembrane system
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 496
Dm

1 489
+ Hs
+ Ce
+ Hs
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025