HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: VIGLN (Q00341)
Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)
Gene: HDLBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	31694235
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1268
+	Hs
		687217 HMGB2_HUMAN (1-187): 7.94e-42: 142: 82.89		VIGLN_HUMAN (1-1268): 0: 937: 100.00
+	Hs
		1024529 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		VIGLN_HUMAN (1-1268): 0: 937: 100.00
+	Hs
		318473 TOX4_HUMAN (91-163): 1.2e-27: 111: 38.36		VIGLN_HUMAN (1-1268): 0: 937: 100.00
+	Hs
		687240 HMGB2_HUMAN (1-187): 7.94e-42: 142: 82.89		PCBP1_HUMAN (968-1148): 1.12e-28: 121: 18.42
+	Hs
		872632 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		FUBP3_HUMAN (361-670): 9.87e-34: 140: 16.92
+	Hs
		1065471 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		IF2B1_HUMAN (833-1226): 3.45e-28: 123: 13.88
+	Hs
		135187 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		IF2B3_HUMAN (70-296): 5.37e-24: 110: 14.62
+	Hs
		872823 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		IF2B1_HUMAN (833-1226): 3.45e-28: 123: 13.88
+	Hs
		872954 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		IF2B2_HUMAN (870-1226): 7.3e-23: 106: 12.57
+	Hs
		1146779 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		PCBP1_HUMAN (968-1148): 1.12e-28: 121: 18.42
+	Hs
		1146974 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		PCBP2_HUMAN (968-1148): 1.53e-27: 118: 18.95