HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: RPN14 (P53196)
26S proteasome regulatory subunit RPN14 (Proteasome non-ATPase subunit 14)
Gene: RPN14

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044183 - protein folding chaperone
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 649 Sc			1 417
+	Hs
		536681 HSP7C_HUMAN (2-649): 0: 947: 72.53		LIS1_HUMAN (132-416): 3.72e-64: 213: 16.34
+	Sc
		528078 HSP72_YEAST (1-649): 0: 941: 78.89		PRP46_YEAST (64-366): 5.6e-45: 163: 15.06
+	Sc
		525619 HSP71_YEAST (1-649): 0: 939: 79.35		PRP46_YEAST (64-366): 5.6e-45: 163: 15.06
+	Hs
		536889 HSP7C_HUMAN (2-649): 0: 947: 72.53		WDR5_HUMAN (217-415): 1.25e-38: 143: 11.50
+	Hs
		537452 HSP7C_HUMAN (2-649): 0: 947: 72.53		WDR5B_HUMAN (208-413): 4.65e-37: 139: 11.11
+	Hs
		222429 HSP7C_HUMAN (2-649): 0: 947: 72.53		PLRG1_HUMAN (41-271): 7.89e-35: 136: 18.46
+	Sc
		481705 HSP73_YEAST (1-649): 0: 948: 100.00		COPA_YEAST (3-403): 1.39e-29: 123: 8.80
+	Sc
		527306 HSP72_YEAST (1-649): 0: 941: 78.89		COPA_YEAST (3-403): 1.39e-29: 123: 8.80
+	Hs
		536814 HSP7C_HUMAN (2-649): 0: 947: 72.53		COPA_HUMAN (3-405): 9.92e-28: 117: 10.11
+	Sc
		524709 HSP71_YEAST (1-649): 0: 939: 79.35		COPA_YEAST (3-403): 1.39e-29: 123: 8.80
+	Hs
		761452 HS71L_HUMAN (2-649): 0: 958: 70.06		POC1A_HUMAN (2-124): 8.16e-22: 98.3: 12.80
+	Hs
		600864 HSP76_HUMAN (4-649): 0: 950: 70.43		POC1A_HUMAN (2-124): 8.16e-22: 98.3: 12.80
+	Sc
		645759 HSP74_YEAST (1-649): 0: 924: 86.75		COPA_YEAST (3-403): 1.39e-29: 123: 8.80
+	Hs
		537531 HSP7C_HUMAN (2-649): 0: 947: 72.53		POC1A_HUMAN (2-124): 8.16e-22: 98.3: 12.80
+	Hs
		537653 HSP7C_HUMAN (2-649): 0: 947: 72.53		FBXW7_HUMAN (316-416): 1.36e-10: 65.1: 14.71
+	Dm
		538293 HSP7D_DROME (2-649): 0: 938: 72.53		FBXW7_DROME (316-414): 2.7e-11: 67.8: 14.00