HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	22119785, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 251
+	Hs
		48493 ESYT2_HUMAN (1-921): 0: 839: 100.00		DERL2_HUMAN (8-249): 5.87e-78: 236: 34.30
+	Hs
		1311375 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		DERL1_HUMAN (1-251): 9.26e-89: 264: 100.00
+	Hs
		1311383 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		DERL2_HUMAN (8-249): 5.87e-78: 236: 34.30