HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HEAT_EZ~HnRNPA1_LC
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 1230
+	Hs
		172146 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		909619 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		650837 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1291156 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1120229 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1291126 DAZP1_HUMAN (3-87): 1.54e-15: 79.4: 31.77		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1102009 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1291181 RBM4_HUMAN (104-187): 6.5e-11: 65.2: 22.35		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Dm
		1064249 SQD_DROME (3-187): 1.1e-52: 179: 32.43		Q9VRV8_DROME (253-1075): 2.21e-28: 125: 11.28
+	Dm
		1064245 SQD_DROME (3-187): 1.1e-52: 179: 32.43		Q9VN44_DROME (175-1181): 1.97e-27: 123: 11.69
+	Hs
		164515 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		TNPO2_HUMAN (432-1148): 1.54e-15: 84.2: 12.59
+	Hs
		485312 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		TNPO1_HUMAN (826-1148): 1.52e-09: 64.6: 12.21
+	Dm
		1171765 Q24024_DROME (11-185): 9.74e-38: 142: 38.83		Q9VN44_DROME (175-1181): 1.97e-27: 123: 11.69
+	Hs
		909646 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		TNPO1_HUMAN (826-1148): 1.52e-09: 64.6: 12.21
+	Hs
		650888 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		TNPO1_HUMAN (826-1148): 1.52e-09: 64.6: 12.21
+	Dm
		462192 ROA1_DROME (89-192): 3.09e-19: 89.8: 23.08		Q9VN44_DROME (175-1181): 1.97e-27: 123: 11.69
+	Hs
		839268 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		MTOR_HUMAN (11-798): 1.43e-22: 107: 11.87
+	Hs
		1120270 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		TNPO1_HUMAN (826-1148): 1.52e-09: 64.6: 12.21