Interactor 1: CDC16 (P09798)
Anaphase-promoting complex subunit CDC16 (Cell division control protein 16)
Gene: CDC16

Interactor 2: CDH1 (P53197)
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1)
Gene: CDH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 9831566, 21107322, 15916960, 39401078, 29883473, 25025567
Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, biochemical
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0031145 - anaphase-promoting complex-dependent catabolic process
GO:0045842 - positive regulation of mitotic metaphase/anaphase transition
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 840
Sc

1 566
+ Sc
+ Sc
+ Hs
+ Sp
+ Sp
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Xl
+ Dm
+ Hs
+ Mm
+ Xl
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025